The PARROT Trial
PARROT is a clinical trial looking to find out whether a 12 month treatment with an antibiotic called azithromycin can reduce how often children with Neurological Impairment (NI) have to stay in hospital with chest infections.
There are large numbers of children with neurological impairment (NI) including conditions such as cerebral palsy. Many are prone to chest infections which can lead to long stays in hospital, possible complications and even premature death.
Despite the impact on children, their families and health services, there is very little information on how best to prevent these severe infections. Some doctors prescribe long-term antibiotics but we don’t really know whether this treatment makes any difference to the numbers of chest infections children suffer from, or whether these antibiotics can cause long term harm.
About the Trial
We are looking for 500 children and young people aged 3-17 years, with NI who are at risk of chest infections to take part.
The trial is taking place in the UK and Australia and each patient will be involved for a maximum of 20 months.
Aims of the PARROT Trial
This trial aims to find out whether 12-month’s treatment with an antibiotic called azithromycin affects: